abstract：BACKGROUND AND OBJECTIVES:Refrigerated storage of red blood cells (RBCs) induces numerous changes that may target the cells for erythrophagocytosis following transfusion. The influence of storage upon the phagocytosis of unseparated and fractionated young and old stored RBCs was investigated using two in vitro quantita...

journal_title：Vox sanguinis

authors： Veale MF,Healey G,Sparrow RL

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Partially replacing plasma with additive solutions in platelet (PLT) concentrates (PCs) may help to reduce transfusion reactions. Constituents of PLT additive solutions (PASs) have been revealed to affect the quality of PCs. Previous studies involved pairwise comparison of identical PLTs with ...

journal_title：Vox sanguinis

authors： Nogawa M,Naito Y,Chatani M,Onodera H,Shiba M,Okazaki H,Matsuzaki K,Satake M,Nakajima K,Tadokoro K

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This report describes a method for estimating the risk of transfusion-transmitted HBV infection attributable to blood components from donors with occult hepatitis B virus infection (OBI) applicable where universal anti-HBc screening is not performed. MATERIALS AND METHODS:In the context of pa...

journal_title：Vox sanguinis

authors： Seed CR,Kiely P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated isometric muscle tension (applied tension) during blood donation reduces vasovagal symptoms in many donors. Experiencing vasovagal symptoms has been found to reduce blood donor return. However, does practicing applied tension improve blood donor return? Follow-up results from a random...

journal_title：Vox sanguinis

authors： Ditto B,Gilchrist PT,Holly CD,Dubuc S,Delage G,France CR

更新日期：2013-11-01 00:00:00

abstract：:Since 2000, Quality Assurance (QA) exercises for the detection and identification of granulocyte antibodies and DNA typing for human neutrophil antigens (HNA) have been distributed within the International Granulocyte Immunobiology Workshops, which are linked to International Society of Blood Transfusion. The exercise...

journal_title：Vox sanguinis

authors： Lucas G,Porcelijn L,Fung YL,Green F,Reil A,Hopkins M,Schuller R,Green A,de Haas M,Bux J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:HPA-1a antibodies account for 70-80% of cases of fetal-neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians. However, numerous workshops have demonstrated variability in their detection. We recently showed that exposure of αIIbβ3 to ethylene diamine tetraacetic acid (EDTA) affected bindi...

journal_title：Vox sanguinis

authors： Allen DL,Metcalfe P,Kaplan C,Kekomaki R,de Haas M,Yusuf R,Ouwehand WH

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Bleeding is increasingly considered an important end point in clinical platelet transfusion studies. Accurate recording and adjudication into well-defined bleeding grades, however, remains a major challenge. METHODS:We developed a computer algorithm for automatic adjudication. The algorithm's results were...

journal_title：Vox sanguinis

authors： Middelburg RA,Ypma PF,van der Meer PF,van Wordragen-Vlaswinkel RJ,Eissen O,Kerkhoffs JL

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite long being a mainstay in describing platelet activation via degranulation, interlaboratory variation remains an issue in measurement of membrane CD62P by flow cytometry. Our objective was to identify actions that may minimize this variation. MATERIALS AND METHODS:Sixteen laboratories ...

journal_title：Vox sanguinis

authors： Levin E,Serrano K,Devine DV,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2013-07-01 00:00:00

abstract：:Peripheral blood stem cell cryopreservation is associated with cell damage and decreased viability. We evaluated the impact of up to 10 years of cryopreservation (5% DMSO) on viability of CD34(+) cells utilizing graft samples of consecutive patients (2002-2012) with different malignancies who underwent stem cell colle...

journal_title：Vox sanguinis

authors： Abbruzzese L,Agostini F,Durante C,Toffola RT,Rupolo M,Rossi FM,Lleshi A,Zanolin S,Michieli M,Mazzucato M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous data that showed maintenance of reticulocyte percentage in whole blood stored in CPDA-1 have led to the assumption that reticulocyte maturation becomes arrested during refrigerated storage. However, reticulocyte behaviour in red-blood-cell units stored in additive solutions has not ye...

journal_title：Vox sanguinis

authors： Urbina A,Palomino F

更新日期：2013-05-01 00:00:00

abstract：:Nowadays, risk of transfusion-transmitted infection has been substantially minimized by stringent donor eligibility screening and infectious disease testing. However, we report an interdiction of a blood donation containing varicella-zoster virus (VZV) by donor self-reporting of chickenpox. The donor developed varicel...

journal_title：Vox sanguinis

authors： Chan HM,Ho PL,Chan KH,Lin CK,Lee CK

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The membrane transporter ABCB6 has recently been shown to carry the high-frequency red-blood-cell (RBC) antigen Lan. All the Lan- individuals genotyped so far have inherited two recessive null mutations in ABCB6. The finding of a family with the Lan- blood type occurring in two successive gener...

journal_title：Vox sanguinis

authors： Saison C,Helias V,Peyrard T,Merad L,Cartron JP,Arnaud L

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to asse...

journal_title：Vox sanguinis

authors： Bugge HF,Karlsen NC,Oydna E,Rake MM,Wexels N,Bendabenda J,Roald B,Heier HE,Chisuwo L,Jourdan PM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There are conflicting data regarding the therapeutic efficacy of platelets inactivated using amotosalen and ultraviolet A light. We have performed a meta-analysis to summarize the results of different randomized controlled trials (RCT). MATERIALS AND METHODS:Five RCTs reported through March 2...

journal_title：Vox sanguinis

authors： Cid J,Escolar G,Lozano M

更新日期：2012-11-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several pathogen inactivation methods currently applied to therapeutic plasma may result in products with different hemostatic properties. This study aims at evaluating and comparing the hemostatic potential of different therapeutic plasma preparations currently available in France. MATERIALS...

journal_title：Vox sanguinis

authors： Hacquard M,Lecompte T,Belcour B,Geschier C,Jacquot C,Jacquot E,Schneider T

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Serratia marcescens is a gram-negative bacterium that has been implicated in adverse transfusion reactions associated with contaminated platelet concentrates. The aim of this study was to investigate whether the ability of S. marcescens to form surface-attached aggregates (biofilms) could acco...

journal_title：Vox sanguinis

authors： Greco-Stewart VS,Brown EE,Parr C,Kalab M,Jacobs MR,Yomtovian RA,Ramírez-Arcos SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The occurrence of thromboembolic events (TEEs) with intravenous immunoglobulin lots (IVIGs) raised the question of the causative agent for these adverse events. We investigated the predominant plasma proteases in 19 IVIG lots from five manufacturers including three lots associated with adverse...

journal_title：Vox sanguinis

authors： Etscheid M,Breitner-Ruddock S,Gross S,Hunfeld A,Seitz R,Dodt J

更新日期：2012-01-01 00:00:00

abstract：:BACKGROUND  Whole blood (WB) donation encompasses several periods during which some donors faint. Identification of factors associated with fainting during each period should guide intervention strategies. Reducing faint reactions may reduce donor injuries and disability. METHODS  Blood donation was divided into three...

journal_title：Vox sanguinis

authors： Bravo M,Kamel H,Custer B,Tomasulo P

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The non-paired two-arm study compared the in vitro storage characteristics of platelets suspended as concentrates in either 100% plasma or a mixture of additive solution (SSP+™, MacoPharma, Mouveaux, France) and autologous plasma in a 70:30 ratio over a 14-day storage period. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Saunders C,Rowe G,Wilkins K,Holme S,Collins P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Whole blood is stored at room temperature (RT) until processing into components. After separation and filtration, the RCC has to be cooled from RT to +2 - 6°C. Different start times of the cooling process and different cooling rates can be encountered in daily routine. The effect of these parameters of the i...

journal_title：Vox sanguinis

authors： Bontekoe IJ,van der Meer PF,de Korte D

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The low-prevalence Rh antigen, JAL, was named after the index case, Mr. J. Allen. Based on reactivity of seven multi-specific sera with his RBCs, it was apparent that they express at least one additional low-prevalence antigen. The purpose of this study was to investigate the other low-prevalence antigen(s) ...

journal_title：Vox sanguinis

authors： Hue-Roye K,Reid ME,Westhoff CM,Lomas-Francis C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A collaborative study was undertaken to evaluate a replacement World Health Organization International Standard for hepatitis C virus (HCV) RNA for nucleic acid amplification technology (NAT)-based assays. The candidate preparations were calibrated in International Units (IUs). MATERIALS AND ...

journal_title：Vox sanguinis

authors： Baylis SA,Heath AB,Collaborative Study Group.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:National guidelines for monitoring bacterial contamination of blood components were introduced in Germany in 1997. Between 1998 and 2002, numerous measures were implemented to prevent bacterial contamination. This study investigates their impact on contamination rates. MATERIALS AND METHODS:C...

journal_title：Vox sanguinis

authors： Walther-Wenke G,Wirsing von König CH,Däubener W,Heiden M,Hoch J,Hornei B,Volkers P,Working Party on Bacteria Safety in Transfusion Medicine, Advisory Board of the German Ministry of Health, Berlin.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：:Plasmodium falciparum malaria has long been a killer of the young, and has selected for polymorphisms affecting not only erythrocytes, but the immunogenetics of three histocompatibility systems: ABO, human leukocyte antigen (HLA), and CD36. The ABO system is important because the original allele, encoding glycosylatio...

journal_title：Vox sanguinis

authors： Cserti-Gazdewich CM,Mayr WR,Dzik WH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Following a 1994 study showing a high rate of transfusion-associated HIV, Kenya implemented WHO blood safety recommendations including: organizing the Kenya National Blood Transfusion Service (NBTS), stringent blood donor selection, and universal screening with fourth-generation p24 antigen and HIV antibody ...

journal_title：Vox sanguinis

authors： Basavaraju SV,Mwangi J,Nyamongo J,Zeh C,Kimani D,Shiraishi RW,Madoda R,Okonji JA,Sugut W,Ongwae S,Pitman JP,Marum LH

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Refractoriness to platelet transfusion because of HLA antibodies can jeopardize the outcome of patients who require platelet support during surgery. As routine screening for HLA antibodies would pose a huge burden on presurgical work-ups, a stratification of patients according to the risk of having HLA antib...

journal_title：Vox sanguinis

authors： Sanz C,Ghita G,Franquet C,Martínez I,Pereira A

更新日期：2010-10-01 00:00:00

abstract：:Platelet function in thrombosis and haemostasis is reasonably well understood at the molecular level with respect to the proteins involved in cellular structure, signalling networks and platelet interaction with clotting factors and other cells. However, the natural history of these proteins has only recently garnered...

journal_title：Vox sanguinis

authors： Schubert P,Devine DV

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies to antigens in the Kell blood group system, especially anti-KEL1, are involved in both haemolytic disease of the newborn and foetus and haemolytic transfusion reactions. Correct typing results are important and discrepancies between serologic and genetic typing must be resolved. Her...

journal_title：Vox sanguinis

authors： Wester ES,Steffensen R,Ligthart PC,Vad J,de Haas M,Storry JR,Olsson ML

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The German Armed Forces Blood Service in Koblenz supplies red blood cell concentrates (RBCs) to military and civilian institutions at home and to field hospitals during peacekeeping operations abroad. During long-distance transport, blood products can be exposed to extreme environmental condit...

journal_title：Vox sanguinis

authors： Klose T,Borchert HH,Pruss A,Roth WK,Bohnen HR,Putzker M

更新日期：2010-07-01 00:00:00

abstract：:There is an ongoing debate whether platelet concentrates (PCs) prepared from either whole-blood donations or by plateletpheresis are superior. Usage of these two product types varies greatly between countries and individual institutions. Some use mainly apheresis PCs; others prefer pooled PCs which are produced from w...

journal_title：Vox sanguinis

authors： Schrezenmeier H,Seifried E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of the study was to replace the 1(st) World Health Organization International Standard for parvovirus B19 DNA for nucleic acid amplification technique (NAT)-based assays (code 99/800). Two lyophilized preparations (coded 99/800 and 99/802) had been evaluated in the original collaborati...

journal_title：Vox sanguinis

authors： Baylis SA,Chudy M,Blümel J,Pisani G,Candotti D,José M,Heath AB

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The low prevalence antigen, Be(a), is produced by a complex that also produces weak c, e and f (ce). We report here the molecular basis associated with Be(a) antigen expression. MATERIALS AND METHODS:Peripheral blood samples from four Be(a+) probands were tested. Haemagglutination, gDNA extra...

journal_title：Vox sanguinis

authors： Hue-Roye K,O'Shea K,Gillett R,Wadsworth LD,Hume H,Barnes J,Kinney J,Hodgins K,Fuchisawa A,Lomas-Francis C,Reid M

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The Mirasol Pathogen Reduction Technology System (PRT) for Plasma (CaridianBCT) is based on a riboflavin and UV light treatment process resulting in pathogen inactivation due to irreversible, photochemically induced damage of nucleic acids. This study evaluated the in vitro protein quality of plasma products...

journal_title：Vox sanguinis

authors： Bihm DJ,Ettinger A,Buytaert-Hoefen KA,Hendrix BK,Maldonado-Codina G,Rock G,Giclas PC,Goodrich RP

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:There are two presumed mechanisms for the pulmonary oedema in transfusion-related acute lung injury (TRALI). One is antibodies to leucocytes while the other is biologically active lipids. We evaluated the vascular injury due to the former. METHODS:The pulmonary vasculature was studied by light microscopy (L...

journal_title：Vox sanguinis

authors： Jensen HM,Galante JM,Kysar PE,Tolstikov VV,Reddy KJ,Holland PV

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Packed red blood cell transfusion has been associated with increased infection in a variety of critically ill patient populations. We evaluated the microbiology and time course of infection in transfused patients in the intensive care unit (ICU) as no data exist on these parameters. MATERIALS...

journal_title：Vox sanguinis

authors： Rachoin JS,Daher R,Schorr C,Milcarek B,Parrillo JE,Gerber DR

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Human platelet growth factors (HPGF) are essential for tissue regeneration and may replace fetal bovine serum (FBS) in cell therapy. No method for the manufacture of standardized virally inactivated HPGF has been developed yet. STUDY DESIGN AND METHODS:Platelet concentrates (PC) were subjected to solvent/de...

journal_title：Vox sanguinis

authors： Su CY,Kuo YP,Lin YC,Huang CT,Tseng YH,Burnouf T

更新日期：2009-08-01 00:00:00